Abstract Background Overcoming the notorious apoptotic resistance of melanoma cells remains a therapeutic challenge given dismal survival of patients with metastatic melanoma.However, recent clinical trials using a BRAF inhibitor revealed encouraging results for patients with advanced BRAF mutant bearing melanoma, but drug resistance accompanied by
Sarcastic remarks on social media platforms have become commonplace, with people expressing Colognes their bad feelings in a quite positive manner or in a mocking way.This contradictive nature of sarcasm makes its detection a very challenging task.Many researchers have provided their solutions to perform automatic sarcasm detection from a single do
The article deals with holiday as social institute, stages of its institutionalization, such as emergence of need; formation of general objects and ideology proving them; development of social norms and rules;practical adoption of rules and procedures; establishment sanction system; creation of statuses and role system.On the example of Dinner Set